April 17, 2023 - mRNA therapeutics

Credo Casmil (Blakney Lab): Expanding the repertoire of self-amplifying RNA vectors based on alphaviruses

Dr. Miffy Cheng/ Dr. Jerry Leung (Cullis Lab): Induction of Bleb Structures in Lipid Nanoparticle Formulations of mRNA Dramatically Improves Transfection Potency

Dr. Nicolas Salcedo (Jan Lab): Functional RNA discovery in dicistroviruses through metagenomic data analysis

Dr. Ying Tam (Acuitas): Lipid Nanoparticulate Delivery Systems to Enable Messenger RNA Medicines

July 17, 2023 - RNA and Disease

Eva Momchilova (Audas Lab): The Role of Ribosomal Intergenic Spacer RNA in Physiological Amyloid Formation

Al Rohet Hossain (Greenblatt Lab): Understanding the role of RNA binding proteins in autism spectrum disorders using Drosophila development

Michael Lizardo (Sorensen Lab): The eIF4A1/2 small molecule inhibitor CR-1-1B down-regulates the antioxidant response in metastatic OS cells and inhibits lung metastasis in vivo.

Owen Daly (Genevant Sciences): Tuning Lipid Nanoparticles for Specific Applications

Oct 16, 2023 - Non-coding RNA

Quinn Abram (Sagan Lab): Elucidating the RNA and protein interactions that underlie (+)-strand synthesis in Zika virus

Maria Jose Navarro Cobos (Brown Lab): Domains of XIST for establishing heterochromatin and silencing.

Samira Ebrahimi (Unrau Lab):

Daniel Kurek (Nanovation Therapeutics): Next-generation LNP technology for extrahepatic gene delivery

March 18, 2024 - RNA modifications

Dr. Zhen Jin (Ly Vu Lab): High-Resolution m6A Mapping in Human Hematopoietic Stem/Progenitor Cells

Renessa Gomes (Ly Vu Lab): Novel Therapeutic Targeting in Acute Myeloid Leukemia (Flash Talk)

Jenny Zhong (Gregg Morin Lab): Identification of alternatively spliced proteoforms in a leukemia cell line with the SF3B1-K700E mutation using short-read RNA-sequencing and shotgun proteomics

Dr. Andrew Varley (UBC RNA Core): RNA Modifications: Chemical vs. Enzymatic Synthesis

Kristy Ramsey & Laurena Mack (Lexogen): Unlocking the Transcriptomic Universe: A Revolution in Single-Cell RNA Sequencing

May 13, 2024

Ziwei Cai (Syam Somasekharan Lab): Investigating the role of the RNA-binding protein DEAD box ATPase DDX55 in castration-resistant prostate cancer

Amrita (Neil Cashman Lab): An oocyte model of TDP-43 toxicity implicates impaired translation as a major disease mechanism in ALS

Dr. Amani Hariri (Amani Hariri Lab): Advancing DNA-based real-time optical sensors for precision diagnostics

Petra Schreiner (Genevant): Optimizing Lipid Nanoparticles for Delivery in Primates

August 7, 2024 -Summer Career Event

An industry talk featuring our sponsor TriLink Biotechnologies - Dr. Ben Hudson (30 min)

Career Panel Discussion Featuring:

• Dr. Ben Hudson (TriLink)

• Dr. Julie Wong (New England Biolabs)

• Dr. Kent Chen (Genevant)

• Dr. Cedric Brimacombe (Polymorphic BioScience Inc.)

• Dr. Andrew Varley (UBC RNA Core)

• Dr. Chris Barbosa (Acuitas)

September 16, 2024

Blakney lab: Dr. Suiyang Liao - “Lipid nanoparticle design from mRNA vaccines to therapeutics”

Morin Lab: Dr. Krysta Coyle - “Uncovering a role for splicing factor mutations in B cell lymphomas”

Adams Lab: Dr. Keith Adams - “Gene expression and alternative splicing in response to Sclerotinia infection in Brassica genotypes”

Acuitas: Polina Blagojevic - “Imagining new ionizable lipids for RNA delivery”